Events | TRITON-TIMI-38 [43] | PLATO [44] | ||||
Prasugrel | Clopidogrel | P-value | Tricagrelor | Clopidogrel | P-value | |
Death MI or stroke% | 9.9 | 12.1 | <0.001 | 10.2 | 12.3 | <0.001 |
Death from cardiovascular cause | 2.1 | 2.4 | 0.31 | 4.0 | 5.1 | 0.001 |
Major bleeding (TIMI) non CABG | 2.4 | 1.8 | 0.03 | 7.9 | 7.7 | 0.57 |
Fatal bleeding | 0.4 | 0.1 | 0.002 | 0.3 | 0.30 | 0.66 |
Intracranial bleeding | 0.3 | 0.3 | 0.74 | 0.3 | 0.2 | 0.06 |